Potential of Orchids Secondary Metabolites as Anti-Cancer and Antimicrobial Based on Prediction of Phytochemical Activity with Online PASS-Software

Abstract
 Orchidology is part of the branch botany, it deals with a large family monocotyledonous plants, Orchidaceae. Orchids have been used as traditional herbal medicines in Indonesia which are believed to be antimicrobial and anti-cancer. able produce secondary metabolites their protective agent due extreme environment. great diversity potential object research, not only experimental studies but also computational like silico. Nowadays, molecular or metabolite data available on official-standard website an international database. This study was conducted by analyzing web-based provide information about orchids that trusted medicines. In this study, from Vanilla spp., Dendrobium Vanda were selected existing literature anti-cancer drugs. Secondary obtained KNApSAck-3D core system Phytochemical Prediction Substance Activity Spectrum (PASS) performed determine activity. Based silico analysis through PASS online, antimicrobials Dendroside E Dendromonilised D Parviflorin, Licoisoflavone Luteine ​​extracted spp. The planifolia has for further research 4-Hydroxybenzoic acid Chlordecone reductase inhibitor extracted shoots. 
 Keywords: orchid, antimicrobial, anticancer, metabolite, online